Compounded GLP-1 + B12
Start with a plan designed around appetite control, tolerability, and follow-up.
Personalized care
Personalized treatment based on your biomarkers & genes.
Most weight-loss plans fail because they treat everyone the same. First Dose uses your intake, biomarkers, and genetic context to help identify the plan you are most likely to tolerate and stick with.
Biomarker Review
Use key lab signals to avoid treating your body like everyone else’s.
Gene-Guided Plan
Use genetic context to flag dose fit, side-effect risk, and poor-response patterns.
Side-Effect Support
Support nausea, hydration, constipation, fatigue, and lean-mass preservation from day one.
Your plan starts here
Find your match.
Not sure which option fits? That is the point — start with the intake and we will help you land on the right plan.
Speak With Us
The real pain
The problem is not willpower. It is mismatch.
When the drug, dose, or support plan does not match your biology, you pay for it with nausea, fatigue, stalls, muscle loss, and weeks you cannot get back.
Tell us your story
Side effects, stalls, dose history
We match your biology
Genes, biomarkers & intake
Start with a clear plan
Built for what you tolerate
Our research
GLP-1 side-effect science, published and in progress.
Our team publishes findings on making GLP-1 treatment more tolerable — from in-silico modeling to clinic-backed mitigation strategies. Read the full research blog at sideeffect.me.
Free consultation
Stop guessing the next dose.
Share your history in about two minutes. We review every submission and follow up if there is a fit.
- 2-minute intake
- No obligation
- Reviewed by our clinical team